WEGNER'S GRANULOMATOSIS-DIAGNOSIS

SUMMARY

1. Affects kidney, lungs, and sinuses.

2. Consider GPA in any patient who presents with a purulent nasal discharge, epistaxis, and/or signs of a glomerulonephritis with hematuria.

3. The patient typically is not dyspneic and may not have a cough or hemoptysis.

4. If you see a similar presentation but ANCA-negative, think anti-glomerular basement membrane disease.

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].