PH & BUFFERING-RENAL BICARBONATE CONTROL
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SUMMARY
3 methods by which the kidneys increase plasma bicarbonate:
1. Reabsorption of filtered bicarbonate: at the proximal tubule & collecting duct
2. Replacement of filtered phosphate with bicarbonate produced by tubular cells
3. Generation of new bicarbonate by glutamine metabolism within tubular cells
Image: Cassandra Uy, McMaster Pathiphysiology. [Accessed 7 Apr. 2019].
Reference(s)
Barrett, K.E., Barman, S.M., Brooks, H.L., X, J. and Ganong, W.F. (2019). Ganong’s review of medical physiology. 26th ed. New York: Mcgraw-Hill Education
