AXONAL TRANSPORT

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SUMMARY

1. Proteins are manufactured in the cell body and transported down the axons by axoplasmic flow.

2. Wallerian degeneration: if the axon is cut, the part distal to the cut degenerates.

3. Dynein, a protein facilitates retrograde transport along the axon.

4. Kinesin, a protein facilitates orthograde transport along the axon.

5. There are 2 types of transport: fast (400 mm/day) & slow (0.5-10 mm/day).


Reference(s)

Barrett, K.E., Barman, S.M., Brooks, H.L., X, J. and Ganong, W.F. (2019). Ganong’s review of medical physiology. 26th ed. New York: Mcgraw-Hill Education