SYSTEMIC SCLEROSIS-GI

SUMMARY

1. Diffuse SSC: wide-mouthed diverticula.

2. Limited SSC: eusophageal dysmotility.

3. Both types: gastroparesis, GORD, chronic esophagitis, strictures, Barrett disease, dysphagia, pseudo-obstruction, malabsorption.

4. Mucosal telangiectasias may be present throughout the GIT. Telangiectasias in the stomach can lead to bleeding and iron-deficiency anemia. This syndrome is called gastric antral vascular ectasia (GAVE).

5. Treat with PPI and prokinetics such as erythromycin.

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].