Difference between revisions of "AUTOREGULATION-PRINCIPLES"
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===== [[Summary Article|'''SUMMARY''']] ===== | ===== [[Summary Article|'''SUMMARY''']] ===== | ||
1. Regulation exists to control and direct blood flow (BF) to vital organs when necessary (brain, heart, kidneys).2. Linear relationship between metabolic rate (MR) & BF ⟹ 8x increase MR in skeletal muscle is assoc. with 4x increase in BF. | 1. Regulation exists to control and direct blood flow (BF) to vital organs when necessary (brain, heart, kidneys). | ||
<br/>2. Linear relationship between metabolic rate (MR) & BF ⟹ 8x increase MR in skeletal muscle is assoc. with 4x increase in BF. | |||
<br/> | <br/> | ||
<br/><i>CONTROL</i> | <br/><i>CONTROL</i> | ||
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==Reference(s)== | ==Reference(s)== | ||
Barrett, K.E., Barman, S.M | Barrett, K.E., Barman, S.M., Brooks, H.L., X, J. and Ganong, W.F. (2019). Ganong’s review of medical physiology. 26th ed. New York: Mcgraw-Hill Education | ||
[[Category:Autoregulation]] | [[Category:Autoregulation]] | ||
[[Category:Physiology]] | [[Category:Physiology]] | ||
Latest revision as of 02:30, 21 March 2023
SUMMARY
1. Regulation exists to control and direct blood flow (BF) to vital organs when necessary (brain, heart, kidneys).
2. Linear relationship between metabolic rate (MR) & BF ⟹ 8x increase MR in skeletal muscle is assoc. with 4x increase in BF.
CONTROL
3. Local BF control: by autoregulation (via myogenic response) & locally produced vasodilator metabolites.
4. Systemic BF control: sympathetic nerves & circulating vasoactive substances.
5. Long-term BF control occurs by changes in the number & size of blood vessels.
Reference(s)
Barrett, K.E., Barman, S.M., Brooks, H.L., X, J. and Ganong, W.F. (2019). Ganong’s review of medical physiology. 26th ed. New York: Mcgraw-Hill Education
