Difference between revisions of "NEUROPATHY-GENERALIZED WEAKNESS"
(Imported from text file) |
(Imported from text file) |
||
| Line 4: | Line 4: | ||
<br/>2. Multifocal Motor Neuropathy (MMN): pure motor, reflexes sometimes preserved, even brisk “oligo-focal” (may be able to identify individual involved nerves), NCS shows conduction block at unusual sites (i.e. not at wrist, elbow, etc.), anti-GM1 antibodies present. | <br/>2. Multifocal Motor Neuropathy (MMN): pure motor, reflexes sometimes preserved, even brisk “oligo-focal” (may be able to identify individual involved nerves), NCS shows conduction block at unusual sites (i.e. not at wrist, elbow, etc.), anti-GM1 antibodies present. | ||
<br/> | <br/> | ||
<br/>3. MND: pure motor, usually mix of UMN & LMN signs, bulbar & respiratory involvement. | <br/>3. MND: pure motor, usually mix of UMN & LMN signs, bulbar & respiratory involvement. | ||
<br/> | <br/> | ||
<br/>4. MG: pure motor, fatigability, bulbar & respiratory, ptosis & diplopia involvement, repetitive stim (or single-fibre EMG in involved muscles). | <br/>4. MG: pure motor, fatigability, bulbar & respiratory, ptosis & diplopia involvement, repetitive stim (or single-fibre EMG in involved muscles). | ||
Latest revision as of 02:29, 21 March 2023
SUMMARY
1. CIDP: often proximal weakness, reasonably symmetrical, absent reflexes, can have a mix of motor and sensory involvement, demyelinating pattern on NCS (including block), neuropathic picture on EMG.
2. Multifocal Motor Neuropathy (MMN): pure motor, reflexes sometimes preserved, even brisk “oligo-focal” (may be able to identify individual involved nerves), NCS shows conduction block at unusual sites (i.e. not at wrist, elbow, etc.), anti-GM1 antibodies present.
3. MND: pure motor, usually mix of UMN & LMN signs, bulbar & respiratory involvement.
4. MG: pure motor, fatigability, bulbar & respiratory, ptosis & diplopia involvement, repetitive stim (or single-fibre EMG in involved muscles).
Reference(s)
Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].
