Difference between revisions of "RENAL PHYSIOLOGY-FRACTIONAL EXCRETION OF SODIUM"
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===== [[Summary Article|'''SUMMARY''']] ===== | ===== [[Summary Article|'''SUMMARY''']] ===== | ||
1. The fractional excretion of sodium (FE<sub>Na</sub>) is the ratio of excreted Na<sup>+</sup> to the total filtered load of Na<sup>+</sup>. | 1. The fractional excretion of sodium (FE<sub>Na</sub>) is the ratio of excreted Na<sup>+</sup> to the total filtered load of Na<sup>+</sup>. | ||
<br/>2. It is used to differentiate prerenal azotemia (FE<sub>Na</sub> < I%, high levels of nitrogen-containing compounds such as creatinine and urea) from acute tubular necrosis (FE<sub>Na</sub> > 2%, ATN). | <br/>2. It is used to differentiate prerenal azotemia (FE<sub>Na</sub> < I%, high levels of nitrogen-containing compounds such as creatinine and urea) from acute tubular necrosis (FE<sub>Na</sub> > 2%, ATN). | ||
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==Reference(s)== | ==Reference(s)== | ||
Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. | Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. [https://amzn.to/3YHrI6K Get it on Amazon.] | ||
<br/>Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. [https://amzn.to/3k7WSW0 Get it on Amazon.] | |||
<br/>Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy. | <br/>Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy. | ||
<br/>Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021]. | <br/>Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021]. | ||
Latest revision as of 20:03, 13 March 2023
SUMMARY
1. The fractional excretion of sodium (FENa) is the ratio of excreted Na+ to the total filtered load of Na+.
2. It is used to differentiate prerenal azotemia (FENa < I%, high levels of nitrogen-containing compounds such as creatinine and urea) from acute tubular necrosis (FENa > 2%, ATN).
3. Other causes of AKI with FENa < I% include: contrast induced ATN, cardio-renal syndrome, hepato-renal syndrome, non-oliguric ATN, pigment nephropathy & acute glomerulonephritis.
Reference(s)
Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].
