MEDICATION-ADRENALINE

1. Naturally occurring catecholamine with alpha (vasoconstriction) & beta effects.

2. Administer in the setting of cardiac arrest to cause vasoconstriction and to redirect available CO to the myocardium & brain.

3. It raises diastolic pressure thereby improving coronoary perfusion and facilitating defibrillation by improving myocardial blood flow during CPR.

4. Indications: asystole, PEA, pulseless VT/VF, bradycardia unresponsive to atropine.

5. Given IM in the setting of anaphylaxis: 0.5 mg every 15 min.

6. SE: tachycardia, HTN, arrhythmias, tissue necrosis if extravasation occurs, hyperglycaemia.

DOSAGE

7. Administer 1 mg every second loop of CPR (1:10,000 via IV cannula or 1:1000 via central line).

8. Infusion of 1-20 mcg/min in ICU.