Difference between revisions of "HYPOTHYROIDISM-INVESTIGATIONS"
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===== [[Summary Article|'''SUMMARY''']] ===== | ===== [[Summary Article|'''SUMMARY''']] ===== | ||
1. High TSH (> 10 mU/L) + low free T<sub>4</sub> ⟹ primary (thyroid) hypothyroidism. | 1. High TSH (> 10 mU/L) + low free T<sub>4</sub> ⟹ primary (thyroid) hypothyroidism. | ||
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<br/>2. High TSH (5-10 mU/L) + normal free T<sub>4</sub> ⟹ subclinical hypothyroidism. TSH drifts up as we age & gain weight. Patients with TSH 5-10mU/L will develop hypothyroidism at the rate of 4%/year. Risks: family hx of autoimmune thyroid disease & anti-TPO Ab. | <br/>2. High TSH (5-10 mU/L) + normal free T<sub>4</sub> ⟹ subclinical hypothyroidism. TSH drifts up as we age & gain weight. Patients with TSH 5-10mU/L will develop hypothyroidism at the rate of 4%/year. Risks: family hx of autoimmune thyroid disease & anti-TPO Ab. | ||
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<br/>3. Low/normal TSH + low free T<sub>4</sub> ⟹ secondary (pituitary)/tertiary (hypothalamus) hypothyroidism. assoc. with deficiency of multiple hormones. Image the sella. | <br/>3. Low/normal TSH + low free T<sub>4</sub> ⟹ secondary (pituitary)/tertiary (hypothalamus) hypothyroidism. assoc. with deficiency of multiple hormones. Image the sella. | ||
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<br/><i>OTHER ABNORMALITIES</i> | <br/><i>OTHER ABNORMALITIES</i> | ||
Latest revision as of 02:29, 21 March 2023
SUMMARY
1. High TSH (> 10 mU/L) + low free T4 ⟹ primary (thyroid) hypothyroidism.
2. High TSH (5-10 mU/L) + normal free T4 ⟹ subclinical hypothyroidism. TSH drifts up as we age & gain weight. Patients with TSH 5-10mU/L will develop hypothyroidism at the rate of 4%/year. Risks: family hx of autoimmune thyroid disease & anti-TPO Ab.
3. Low/normal TSH + low free T4 ⟹ secondary (pituitary)/tertiary (hypothalamus) hypothyroidism. assoc. with deficiency of multiple hormones. Image the sella.
OTHER ABNORMALITIES
4. Hyponatremia
5. Normochrmic/normocytic anemai
6. Hyperlipidemia
7. Pericardial effusions on echo
Reference(s)
Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].
