Difference between revisions of "LAMBERT EATON SYNDROME-INVESTIGATION"
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===== [[Summary Article|'''SUMMARY''']] ===== | ===== [[Summary Article|'''SUMMARY''']] ===== | ||
1. Voltage-gated calcium channel antibodies (anti-VGCC) | 1. Voltage-gated calcium channel antibodies (anti-VGCC): not 100% specific. Measure only in those with high pre-test probability. | ||
<br/> | <br/> | ||
<br/>2. EMG | <br/>2. EMG: decremental response (weakening) to rapid stimulation in MG and incremental response (strengthening) in LE syndrome. | ||
<br/> | <br/> | ||
<br/>3. Check for malignancy | <br/>3. Check for malignancy: SCC. | ||
Latest revision as of 02:29, 21 March 2023
SUMMARY
1. Voltage-gated calcium channel antibodies (anti-VGCC): not 100% specific. Measure only in those with high pre-test probability.
2. EMG: decremental response (weakening) to rapid stimulation in MG and incremental response (strengthening) in LE syndrome.
3. Check for malignancy: SCC.
Reference(s)
Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].
