Difference between revisions of "MYOPATHY-TYPES"
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===== [[Summary Article|'''SUMMARY''']] ===== | ===== [[Summary Article|'''SUMMARY''']] ===== | ||
1. Inflammatory myopathies | 1. Inflammatory myopathies: caused by chronic muscle inflammation. Causes: dermatomyositis, polymyositis, IBD. | ||
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<br/>2. Endocrine myopathy | <br/>2. Endocrine myopathy: proximal muscle weakness of varying degrees may be seen in patients with hyperthyroidism, acromegaly, severe vitamin D deficiency, and conditions of steroid excess. | ||
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<br/>3. Metabolic myopathy | <br/>3. Metabolic myopathy: consider in patients with muscle fatigue, pain, cramping, contractures and myoglobinuria exacerbated by exercise. Caused by disorders of carbohydrate, lipid metabolism or mtochondrial function. | ||
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<br/>4. Muscular dystrophy | <br/>4. Muscular dystrophy: genetic abnormalities. Duchenne muscular dystrophy: X-linked disorder that causes progressive muscle weakness, starting at 2yrs, and progressing to death as a young adult. Myotonic dystrophy consists of 2 types of inherited, adult-onset, neuromuscular disorders with systemic effects. | ||
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<br/>5. AlDS-related myopathy is uncommon and typically thought to be due to zidovudine (ZDV, AZT). | <br/>5. AlDS-related myopathy is uncommon and typically thought to be due to zidovudine (ZDV, AZT). |
Latest revision as of 02:29, 21 March 2023
SUMMARY
1. Inflammatory myopathies: caused by chronic muscle inflammation. Causes: dermatomyositis, polymyositis, IBD.
2. Endocrine myopathy: proximal muscle weakness of varying degrees may be seen in patients with hyperthyroidism, acromegaly, severe vitamin D deficiency, and conditions of steroid excess.
3. Metabolic myopathy: consider in patients with muscle fatigue, pain, cramping, contractures and myoglobinuria exacerbated by exercise. Caused by disorders of carbohydrate, lipid metabolism or mtochondrial function.
4. Muscular dystrophy: genetic abnormalities. Duchenne muscular dystrophy: X-linked disorder that causes progressive muscle weakness, starting at 2yrs, and progressing to death as a young adult. Myotonic dystrophy consists of 2 types of inherited, adult-onset, neuromuscular disorders with systemic effects.
5. AlDS-related myopathy is uncommon and typically thought to be due to zidovudine (ZDV, AZT).
Reference(s)
Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].