Difference between revisions of "ANTIBODIES-ANTINUCLEAR ANTIBODIES"

Latest revision as of 20:03, 13 March 2023

SUMMARY

1. Autoimmune antibodies that attack components of the nucleus, found in many autoimmune disorders.

2. Titers show the dilution at which the antibodies become undetectable. It is shown in doublings: 1:40, 1:640, etc. So, the higher the titer, the more antibodies in the serum; positive if > 1:80.

3. While ANA patterns may provide some information, they do not identify the specific antibody present, nor are they specific for any particular disease.

4. Positive in drug-induced lupus, SLE, mixed CT diseases, diffuse systemic sclerosis, polymyositis, RA.

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].

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 ==Reference(s)==
-Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
+Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. [https://amzn.to/3YHrI6K Get it on Amazon.]
+<br/>Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. [https://amzn.to/3k7WSW0 Get it on Amazon.]
 <br/>Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
 <br/>Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].