View source for MULTIPLE SCLEROSIS-FATIGUE MANAGEMENT

===== [[Summary Article|'''SUMMARY''']] =====
1. Subjective lack of mental &amp; physical capacity to perform usual duties; 78-87% of MS patients experience fatigue.
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<br/>2. Self-absorbing and all-consuming phenomenon! Worse with heat and after meals, a rise of ≥ 0.5<sup>o</sup>C results in heat-related fatigue (Uhthoff's phenomenon).
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<br/>3. Assessment scales: fatigue-severity scale, fatigue-descriptive scale, fatigue-impact scale. 
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<br/>4. DDx for fatigue: low-level of fitness (secondary fatigue), poor sleep hygiene, hypothyroidism, sedative medications such as Baclofen.
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<br/>5. Non-pharmacologic management most effective: energy-conservation techniques, pacing, patient/family education, adaptive equipment, work-simplification, home modifications, aerobic exercise, sleep hygiene, lifestyle modifications.
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<br/>6. Pharmacologic management: amantadine, modafinil, fampridine.


==Reference(s)==
Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. [https://amzn.to/3YHrI6K Get it on Amazon.]
<br/>Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. [https://amzn.to/3k7WSW0 Get it on Amazon.]
<br/>Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
<br/>Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].

[[Category:Multiple Sclerosis]]
[[Category:Neurology]]
[[Category:Medicine]]