View source for AUTOREGULATION-NITRIC OXIDE (NO) FUNCTIONS

===== [[Summary Article|'''SUMMARY''']] =====
1. Flow-induced dilation of large arteries by locally produced NO. 
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<br/>2. Plt aggregation releases NO, keeping vessels with intact endothelium patent. 
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<br/>3. Tonic release of NO is necessary to maintain normal BP. 
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<br/>4. Vascular remodelling and angiogenesis. 
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<br/>5. Pathogenesis of arthresclerosis.
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<br/>6. Penile erection.
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<br/>7. Important for brain function (acting via cGMP). 
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<br/>8. Important for cytotoxic activity of macrophages, including their ability to kill cancer cells.
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<br/>9. In GIT, NO causes smooth muscle relaxation.


==Reference(s)==
Barrett, K.E., Barman, S.M., Brooks, H.L., X, J. and Ganong, W.F. (2019). Ganong’s review of medical physiology. 26th ed. New York: Mcgraw-Hill Education 

[[Category:Autoregulation]]
[[Category:Physiology]]